Description

Prontosan Wound Irrigation Solution, developed by B. Braun, is a specialized topical solution designed for comprehensive wound care management. It is expertly formulated to cleanse, rinse, moisten, and decontaminate a variety of wound types, including acute, chronic, and burn wounds. This solution is particularly effective in disrupting and removing biofilm, wound debris, and slough, thereby minimizing infection risks and promoting a more efficient healing process.

Key Features

• Biofilm Management: Prontosan excels in biofilm disruption and removal, enhancing wound bed conditions for improved healing outcomes.
• Antimicrobial Properties: The inclusion of polyhexanide (PHMB) provides broad-spectrum antimicrobial action against both gram-negative and gram-positive bacteria, as well as yeast, including multidrug-resistant strains such as MRSA and VRE.
• Surfactant Action: Contains betaine, which acts as a surfactant to effectively penetrate and clear wound debris and biofilm.

Benefits

• Pain Reduction: Facilitates gentle dressing changes, reducing pain and discomfort during wound care.
• Odor Control: Effectively manages wound odor, enhancing patient comfort.
• Compatibility: Suitable for use with various wound dressings and in conjunction with negative pressure wound therapy.
• Low Cytotoxicity: Offers a balance between antibacterial efficacy and low cell toxicity, ensuring minimal skin irritation.

Clinical Evidence

Prontosan has demonstrated superior performance in clinical studies compared to saline or Ringer’s solution, particularly in wound bed preparation and healing outcomes. It is well tolerated by patients, does not induce skin irritation, and is suitable for a wide range of wounds, including:

• Surgical and traumatic wounds
• Venous leg ulcers
• Diabetic foot ulcers
• Pressure ulcers
• Superficial to deep partial thickness burns

Composition

• Polyhexanide (PHMB): 0.1%
• Betaine: 0.1%
• Purified Water

This colourless, odourless liquid maintains a pH between 6 and 8, is non-flammable, and remains stable under normal conditions. It poses no significant reactive hazards, making it safe for regular use.

Safety and Handling

While generally safe, Prontosan may cause sensitization upon skin contact and eye irritation in susceptible individuals. It is important to store the solution properly, keeping it in a well-ventilated, cool place with the container tightly closed. Disposal should adhere to local regulations to prevent environmental impact.

Directions for Use

Prontosan can be applied by soaking gauze with the solution and placing it on the wound bed to remove debris and disrupt biofilm. It is also suitable for dampening debridement pads for soft mechanical debridement and for rinsing and moistening wounds before dressing changes.

Packaging and Storage

Available in 40 ml ampoules, 350 ml bottles, and 1000 ml bottles, Prontosan offers versatile packaging options. The solution remains stable for up to 8 weeks after opening when used for a single patient, ensuring long-term efficacy and convenience.

Regulatory Status

Prontosan is CE marked as a class III medical device, underscoring its quality and reliability in advanced wound care management.