Description

COPHENYLCAINE FORTE is a specialised nasal spray designed for medical use, combining the effects of a local anaesthetic and a vasoconstrictor. Manufactured by Aspen Pharmacare Australia Pty Ltd, it serves a crucial role in providing topical anaesthesia and local vasoconstriction of the nasal and pharyngeal mucosa. This makes it particularly valuable before diagnostic or surgical procedures involving the upper airways.

Active Ingredients

• Lidocaine Hydrochloride Monohydrate: 50 mg per mL
• Phenylephrine Hydrochloride: 5 mg per mL

These components work together to ensure effective pain relief and reduced bleeding during medical interventions.

Formulation

The product is presented as a clear, colourless liquid in a pump-actuated spray bottle. It is available in various pack sizes, including 2.5 mL, 15 mL, 25 mL, and 50 mL. Each spray delivers 100 microlitres, containing 5 mg of lidocaine and 0.5 mg of phenylephrine. Flexi Nozzles, available in short and long lengths, are provided separately to ensure hygienic application, with a new nozzle recommended for each patient.

Indications

COPHENYLCAINE FORTE is indicated for:

• Preparing the nasal mucosa for procedures such as endoscopy and surgery
• Managing acute nosebleeds
• Facilitating the removal of nasal foreign bodies
• Providing pharyngeal anaesthesia prior to laryngoscopy
• Relieving surface pain from minor abrasions and wounds
• Controlling mild to moderate oral or post-tonsillectomy bleeding

Dosage

The dosage varies based on age and intended use, with specific guidelines for adults and children over 2 years. It is crucial to adhere to recommended dosages and consult a physician for repeated applications.

Pharmacological Properties

• Lidocaine: Acts as a local anaesthetic with rapid onset, stabilising neuronal membranes to prevent nerve impulse transmission.
• Phenylephrine: Functions as a vasoconstrictor, reducing systemic absorption of lidocaine, minimising bleeding, and prolonging anaesthetic action.

Contraindications and Precautions

Use is contraindicated in individuals with hypersensitivity to its active ingredients, during pregnancy, and in children under 2 years. Caution is advised for patients with cardiovascular conditions, and those on interacting medications. Potential adverse effects include a transient bitter taste, with rare occurrences of nervousness, nausea, and cardiovascular symptoms.

Storage

Store below 30°C and ensure carton seals are intact before use. The shelf life ranges from 2 to 3 years, depending on the pack size. Proper handling, including the use of a new nozzle for each patient, is essential to prevent cross infection.

Regulatory Information

In Australia, COPHENYLCAINE FORTE is classified as a Schedule 2 Pharmacy Medicine, available without a prescription, though in some contexts it may be prescription-only. It is registered with the Australian Register of Therapeutic Goods (ARTG ID 35208), ensuring compliance with local medical standards.