Description

Carafate Tab, containing 1 g of sucralfate per tablet, is a specialized medication primarily used in the management of gastrointestinal conditions such as duodenal ulcers. As an antiulcer agent, it serves a crucial role in both the short-term treatment of active ulcers and the maintenance therapy of healed ulcers.

Mechanism of Action

Carafate Tab operates locally within the gastrointestinal tract, forming a protective barrier at ulcer sites. This barrier shields the ulcer from stomach acid, pepsin, and bile salts, thereby promoting healing and providing relief. Its unique action minimizes systemic absorption, making it a targeted therapy with reduced systemic effects.

Administration Guidelines

• Dosage: Typically, adults are advised to take 1 g four times daily on an empty stomach. For maintenance therapy, the dosage is reduced to 1 g twice daily.
• Instructions: It should be taken on an empty stomach, ideally one hour before meals. Patients are advised to manage the timing of antacids and other medications to avoid interactions.

Tablet Characteristics

The tablets are light pink, oblong, and scored, with 'CARAFATE' embossed on one side. This design allows for easy splitting if necessary. Tablets can also be crushed and mixed with water for those with swallowing difficulties.

Inactive Ingredients

The formulation includes:

• D & C Red #30 Lake
• FD&C Blue #1 Lake
• Magnesium stearate
• Microcrystalline cellulose
• Corn starch
• Carmellose sodium
• Macrogol 1500

Precautions

Patients with renal impairment or those on dialysis should use Carafate Tab with caution due to the risk of aluminum accumulation. It is also important to monitor blood sugar levels in diabetic patients. While generally considered safe during pregnancy and breastfeeding, consultation with a healthcare provider is recommended.

Potential Side Effects

Common side effects include constipation, while other less frequent reactions may involve gastrointestinal discomfort, dizziness, or skin rash. Patients should be aware of rare hypersensitivity reactions and seek medical attention if they occur.

Storage Instructions

Store Carafate Tab at room temperature, between 15–30°C (59–86°F), in a tightly closed container. Keep it away from moisture, heat, and direct light to maintain its efficacy.

Important Considerations

Carafate Tab is not an antacid and is intended for oral use only. It is not recommended for children under 18 years, and its use should be guided by a healthcare professional to ensure optimal outcomes in ulcer management.